Exploring the underlying causes of orgasm-related pain in endometriosis
As one of the most common symptoms of endometriosis, pain may involve peripheral or central mechanisms resulting in different pain sensations. Female orgasm pain is an underexplored condition associated with pelvic floor myalgia and uterine factors like adenomyosis, likely due to…
Key Points Lay SummaryAn often overlooked symptom: Sleep disorders in patients with endometriosis
Recent reports suggested that women with endometriosis have more frequent complaints of poor sleep, reduced quality of life, and higher pain scores when compared with healthy women. Patients experience fatigue and increased pain the day after insomnia. For this reason,…
Key Points Lay SummaryObjective Assessment of Pain Sensitization in Women With Chronic Pelvic Pain
There are objective elements that can help assess the presence of central sensitization, independently of psychological factors, according to a new study published in the American Journal of Obstetrics and Gynecology. This is the first study that assessed whether central sensitization…
Key Points Lay SummaryThe role of neurogenic inflammation in endometriosis
Prof. Mechsner from Charité—Universitätsmedizin Berlin, Germany presented on neuroimmunomodulation and its clinical impact on endometriosis at the Annual International Medical Conference of the Endometriosis Foundation of America. Endometriosis is a complex disease and the main symptoms are all pain-related. The pain mechanisms are…
Key Points Lay SummaryEndometriosis and the possible mechanisms of pain.
The most common clinical symptoms of endometriosis are chronic pelvic pain and infertility. It is often not enough to treat pain symptoms with hormonal therapy or a surgical approach. Moreover, the stage of endometriosis has weakly associated with the amount,…
Key Points Lay SummaryChronic pelvic pain and endometriosis
Patients may have an average of 7 clinical visits before being diagnosed with endometriosis. Understanding chronic pain conditions including endometriosis-associated pain, and developing chronic pelvic pain benefits the management of the patients. The role of central sensitization, comorbid conditions, and…
Key Points Lay SummaryPersistence of Chronic Pelvic Pain after Hysterectomy
Chronic pelvic pain is defined as the "pain in the pelvic area that lasts for 6 months or longer". There are several gynecological, urological, and gastrointestinal reasons for the development of chronic pelvic pain. Nociceptive pain or central sensitization is…
Key Points Lay SummaryThe clues for pain and infertility in endometriosis/adenomyosis complex
Drs. Gruber and Mechsner from Charite University-Berlin, Germany published their comprehensive review on pathophysiological background of endometriosis and adenomyosis in the scientific periodical “Cells”. Chronic pain and fertility problems are the main clinical issue in endometriosis and adenomyosis patients. In order to…
Key Points Lay SummaryWomen with Persistent Pelvic Pain Have a Lower Pain Threshold
Women with persistent pelvic pain, whether this is caused by endometriosis or other reason, have a significantly reduced pain threshold compared to women without persistent pelvic pain. This is according to a study by researchers in Sweden, which was published…
Key Points Lay SummaryPain Education or Cognitive Therapy Could Help Women with Endometriosis
Women with endometriosis have a significantly lower pain tolerance regardless of the intensity of the pain they experience or the severity of their disease, according to a study published in the scientific journal Fertility and Sterility. Although pain is the…
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